Imerslund–Grasbeck Syndrome (selective B12 malabsorption): Think about it also in Down's syndrome!

Imerslund-Gräsbeck syndrome (selective vitamin B12 malabsorption with proteinuria)

Imerslund-Gräsbeck syndrome (IGS) or selective vitamin B(12) (cobalamin) malabsorption with proteinuria is a rare autosomal recessive disorder characterized by vitamin B(12) deficiency commonly resulting in megaloblastic anemia, which is responsive to parenteral vitamin B(12) therapy and appears in childhood. Other manifestations include failure to thrive and grow, infections and neurological d...

Specific malabsorption of vitamin B12 in Down's syndrome.

A 3 year old girl with Down's syndrome became lethargic and withdrawn, and investigations showed a specific malabsorption of vitamin B12 without proteinuria.

Familial selective malabsorption of vitamin B12.

Malabsorption syndrome in broilers

Malabsorption syndrome (MAS) is a multifactorial disease that causes intestinal disorders in broilers due to infection of the gastrointestinal tract with different infectious agents. The exact aetiology is unknown, although several viruses are isolated from MAS affected chickens. None of these isolated infectious agents alone inducted the malabsorption syndrome. MAS in broilers is characterised...

What pulmonologists think about the asthma–COPD overlap syndrome

BACKGROUND Some patients with COPD may share characteristics of asthma; this is the so-called asthma-COPD overlap syndrome (ACOS). There are no universally accepted criteria for ACOS, and most treatments for asthma and COPD have not been adequately tested in this population. MATERIALS AND METHODS We performed a survey among pulmonology specialists in asthma and COPD aimed at collecting their ...